Institute of Information Science Academia Sinica
Topic: TIGP -- Information hidden in a single structure - how to derive sequence conservation without doing sequence comparison?
Speaker: Dr. Jenn-Kang Hwang (Institute of Bioinformatics, National Chiao Tung University)
Date: 2012-04-05 (Thu) 14:00 – 15:10
Location: Auditorium 106 at new IIS Building
Host: Wen-Lian Hsu

Abstract:

Our recent work showed that it is possible to derive information about function, dynamics and evolution directly from a single protein structure. This can be done without using a mechanical model or methods based on structure or sequence comparison. Our results show that a protein structure is more than just a scaffold holding residues in place and that there is a meaning in every twist and turn in a protein structure.