Jia-Ming Chang

Research Assistant

Intelligent Agent Systems Lab

Institute of Information Science, Academia Sinica

Taipei, Taiwan

Tel: 886-2-2788-3799 ext. 2353

Fax: 886-2-2651-8660

Email: jmchang@iis.sinica.edu.tw

Address: IIS, 128 Academia Road, Section 2, Nankang, Taipei 115, Taiwan

☉ Vita ☉ Education ☉ Experience ☉ Research Interests ☉ Publications
☉ Tools☉ Academic Activities ☉ Extracurricular Activities

Department of Computer Science,
Nation Tsing Hua University, Hsinchu, Taiwan
Thesis: Compact Set Relation and Its Application in the Evaluation of the Evolutionary Tree and Multiple Sequence Alignment.
Supervisor: Prof. Chuan Yi Tang

• Structure bioinformatics: protein secondary structure prediction; NMR backbone assignment
• Protein functional analyses: protein subcellular localization prediction
• Sequence analysis: constrained multiple sequence alignment
• Molecular evolution: evaluation of evolutionary tree
• Design and analysis of discrete algorithms and statistical learning

1. Wu, K.P., Chang, J.M., Chou, W.C., Chen, J.B., Sung, T.Y., Chang, C.F., Wu, W.J., Huang, T.H. and Hsu, W.L. (2006) RIBRA—An Error-Tolerant Algorithm for the NMR Backbone Assignment Problem. Journal of Computational Biology, 13, 229-244.
2. Lin, H.N., Wu, K.P., Chang, J.M., Sung, T.Y. and Hsu, W.L. (2005) GANA—a genetic algorithm for NMR backbone resonance assignment. Nucleic Acids Research, 33, 4593-4601.
3. Lin, H.N., Chang, J.M., Wu, K.P., Sung, T.Y. and Hsu, W.L. (2005) HYPROSP II-A knowledge-based hybrid method for protein secondary structure prediction based on local prediction confidence. Bioinformatics, 21, 3227-3233.
4. Wu, K.P., Lin, H.N., Chang, J.M., Sung, T.Y. and Hsu, W.L. (2004) HYPROSP: a hybrid protein secondary structure prediction algorithm-knowledge-based approach. Nucleic Acids Research, 32, 5059-5065.
5. Tang, C.Y., Lu, C.L., Chang, M.D.T., Tsai, Y.T., Sun, Y.J., Chao, K.M., Chang, J.M., Chiou, Y.H., Wu, C.M., Chang, H.T. et al. (2003) Constrained Multiple Sequence Alignment Tool Development and Its Application to RNase Family Alignment. Journal of Bioinformatics and Computational Biology, 1, 267-287.
6. Chang, J.M., Su, C.Y., Chiu, H.U., Lo, Allan, Sung, T.Y. and Hsu, W.L. Protein Subcellular Localization Prediction based on based on gapped-dipeptides and probabilistic latent semantic analysis. (Submitted to PROTEINS: Structure, Function, and Bioinformatics, Under Major Revision)
   

1. Yang, E.W., Chang, J.M., Lin, H.N., Sung, T.Y. and Hsu, W.L. (2007) HYPROSP III - A new knowledge-base prediction method for protein secondary structure prediction based on decision fusion. Sixth International Conference on Bioinformatics (InCoB2007) HongKong-Hanoi-Nansha.
2. Wu, K.P., Chang, J.M., Chou, W.C., Chen, J.B., Sung, T.Y., Chang, C.F., Wu, W.J., Huang, T.H. and Hsu, W.L. (2005) RIBRA-an Error-Tolerant Algorithm for the NMR Backbone Assignment Problem. The Ninth Annual International Conference on Research in Computational Molecular Biology (RECOMB 2005), 103-117.
3. Tang, C.Y., Lu, C.L., Chang, M.D.T., Tsai, Y.T., Sun, Y.J., Chao, K.M., Chang, J.M., Chiou, Y.H., Wu, C.M., Chang, H.T. et al. (2002) Constrained Multiple Sequence Alignment Tool Development and Its Application to RNase Family Alignment. Proceedings of the First IEEE Computer Society Bioinformatics Conference (CSB 2002),127-137. (Times cited:16)
4. Tang, C.Y., Lu, C.L., Chang, M.D.T., Sun, Y.J., Tsai, Y.T., Chang, J.M., Chiou, Y.H., Wu, C.M., Chang, H.T., Chou, W.I. et al. (2002) Constrained Sequence Alignment Tool Development and Its Application to RNase Family Alignment. Proceedings of the 2002 International Conference on Mathematics and Engineering Techniques in Medicine and Biological Sciences (METMBS 2002), 365-370. (Oral presetation)
5. Chang, J.M., Tang, C.Y. and Chang, C.L. (2002) Compact Set Neighboring Relation and Its Application in Evaluating Evolution Tree. Workshop on Algorithms and Computational Molecular Biology, International Computer Symposium (ICS 02)

1. Chang, J.M., Su, Emily C.Y., Lo, Allan, Chiu, H.S., Sung, T.Y. and Hsu, W.L. (2007) A Document Classification Strategy to Predict Protein Subcellular Localization Using Sequence Motifs and Evolutionary Information. Poster at the 15th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB 2007, poster session) *Su, Emily C.Y. was awarded a travel fellowship.
2. Chang, J.M., Su, Emily C.Y., Lo, Allan, Chiu, H.S., Sung, T.Y. and Hsu, W.L. (2007) PSLDoc: Protein Subcellular Localization prediction based on Document classification. Poster at The Eleventh Annual International Conference on Research in Computational Molecular Biology (RECOMB 2007, poster session).