TIGP -- Design and Analytical Approaches for Conducting a Genome-Wide Association Study
- LecturerProf. Su-Wei Chang (Clinical Informatics and Medical Statistics Research Center (CIMS), Chang Gung University)
Host: TIGP Bioinformatics Program - Time2013-03-28 (Thu.) 14:00 ~ 15:10
- LocationAuditorium 106 at new IIS Building
Abstract
In this talk, I will focus on essential issues for designing and conducting a case-control genome-wide association study. An analytical work flow starting with data preparation, sample size and power consideration from both statistical and clinical perspectives will be discussed. The choice of genotyping chips, statistical testing and use of imputation will be evaluated. I will also review the strength, challenges and future opportunities of performing second-generation genome-wide association studies.