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Journal of Inforamtion Science and Engineering, Vol.11 No.2, pp.275-294 (June 1995)
Design of a Self-Adaptive Brain Tumor
Diagnostic System

Ching-Hung Wang#, Shian-Shyong Tseng and Tzung-Pei Hong*
Institute of Computer and Information Science
National Chiao Tung University
Hsinchu, 300, Taiwan, R.O.C.
*Department of Information Management
Kaohsiung Polytechnic Institute
Kaohsiung, 800, Taiwan, R.O.C.
#Directorate General of Telecommunication Laboratories
Ministry of Transportation and Communications
Chung-Li, 320, Taiwan, R.O.C.

This paper presents a self-adaptive expert system for brain tumor diagnosis we have designed. The Brain Tumor Diagnostic System (BTDS) we propose consists of three main components: knowledge building, inference, and knowledge refinement. In the knowledge building component, an inductive learning algorithm, RASSISTANT, constructs an initial knowledge base from noisy examples, eliminating a major difficulty in developing diagnostic expert systems. In the inference component, an inference engine exploits rules in the knowledge base to help diagnosticians determine brain tumor causes according to computer tomography pictures. A simple rule refinement scheme, PCC, is also proposed to modify the existing knowledge base during inference, which dramatically improves the accuracy of the derived rules. BTDS performance has been evaluated on 270 actual brain tumor cases. Results show that BTDS can achieve an accuracy of over 98%.

Keywords: expert systems, machine learning, refinement, brain tumors, diagnosis

Received February 22, 1993; revised December 9, 1994.
Communicated by Wen-Tsuen Chen.