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                 Hsu, Wen-Lian                                 ਿ    ͉   ༟    ࣘ                                                              Research Description
                                                                                                                                            Research Description
                                                               ਿ ͉ ༟ ࣘ

                                                               ᔖcc၈j޼ӺࡰResearch Fellow (1989--)                                             In graph algorithms, we have done extensive   knowledge-based algorithm to improve the accuracy
                                                                                                                                        and groundbreaking work on two fundamental       of protein secondary structure prediction problem
                                                               ௰৷ኪዝj Ph.D., Operations Research,                                        classes of special graphs - planar graphs and inter-  to 82%. We have successfully integrated biological
                                                                         Cornell University (1980)                                      val graphs and their related graphs (such as circular   knowledge and machine learning techniques into
                                                                                                                                        arc graphs and circle graphs). We introduced a new   many structure prediction problems
                                                               ཥcc༑j+886-2-2788-3799 ext. 1804                                          data structure [2], PC-tree, which greatly simpli-
                                                                                                                                                                                             In natural language processing we have de-
                                                                                                                                        fies the recognition of these two classes. PC-trees
                                                               ෂccॆj+886-2-2782-4814                                                                                                     signed a Chinese input system - GOING, which
                                                                                                                                        algorithms can unify the test of the consecutive
                                                                                                                                                                                         automatically translates a phonetic (or Pinyin) se-
                                                               ཥɿڦᇌjhsu@iis.sinica.edu.tw                                               ones property and the circular ones property [10].                                                 Research Fellows
                                                                                                                                        Furthermore, PC-tree is a natural representation for   quence into characters with accuracy close to 96%,
                                                               ၣccࠫjhttp://www.iis.sinica.edu.tw/IASL/hsu/eindex.html                   planar graph embedding. Our new planarity test   is widely used in Taiwan. It received the Distin-
                                                                                                                                                                                         guished Chinese Information Product Award€ʕ
                                                                                                                                        based on PC-trees is simple, elegant and yields a
                                                                                                                                                                                         ˖௫̈༟ৃପۜᆤin 1993. Since 1999, in PC
                                                                                                                                        linear time algorithm for finding maximal planar
                                                                  ޼Ӻᔊʧ                                                                  subgraphs.                                       Home alone, it has been downloaded close to one
                                                                  ޼Ӻᔊʧ
                                                                                                                                                                                         million times. Another achievement is the develop-
               •  Wen-Lian Hsu received a B.S. from the Depart-                                                                             In DNA sequence analysis, we have produced   ment of a knowledge inference kernel, InfoMap, for
                                                                                                                                                                                                                                           Research Fellows
                 m                                                 Ңٙ޼Ӻ˴ࠅމࠇၑ͛يኪɪٙஐͣሯҏΐe                                                 an error-tolerant algorithm for the physical mapping   the semantic analysis of natural language, which can
                 ment of Mathematics, National Taiwan University
                 in 1973. He received an M.S. and a Ph.D. in opera-  ഐ࿴ěঐʱؓd͛ي˖ᘠઞਖdІ್ႧԊଣ༆i                                             and the clone assembly problem, which can accom-  be applied to a wide variety of application systems
                 tions research from Cornell University in 1978 and   ̤̮dɰऒᓳྡሞစၑجfҎૐঐഐΥစၑج˸ʿ
                 1980, respectively. From 1979 to 1980, he worked                                                                       modate four types of errors: false positives, false   in natural language processing, biological knowl-
                 as a research associate in the Center for Operations   ႧԊҏΐʱؓɪٙ຾᜕࿁ஐͣሯҏΐٙจ່Ϟהഹ                                          negatives, chimeric clones and non-unique probes.   edge base, automation of pipeline experiment, and
                 Research and Econometrics (CORE) at Universite   ኈf                                                                    We have also used an iterative relaxation technique   e-learning. In 2005, we won the first place among
                 Catholique de Louvain, Belgium. In 1980, he joined                                                                     to develop an error-tolerant algorithm for the back-  9 teams in the first Chinese Question Answering
                 Northwestern University as an assistant professor   ίྡሞစၑجɪdҢࡁ೯࢝̈ɓࡈ༟ࣘഐ࿴                                                bone assignment problem in NMR protein struc-    contest in NTCIR held in Tokyo, Japan.  In 2006,
                 and was promoted to tenured associate professor in   ˜PC-tree™dঐ੄ɽඎᔊʷ፫Ⴉ̻ࠦྡձਜගྡٙ
                 1986. He joined the Institute of Information Science                                                                   ture determination. Finally, we have developed a   we won the first place among 13 teams for the city
                 as a research fellow in 1989.                 ѢᗭܓfPC-tree̙˸ܘІ್ήڌ༺̻ࠦྡdԨ̙˸                                                                                                U corpus in SIGSAN Chinese Word Segmentation
                                                               ୕Υஹᚃɓၾᐑًɓٙ፫ᗆfҢࡁл͜PC-treeהண                                                                                                Contest.
               •  Right after joining IIS in 1989, he initiated the proj-  ࠇ̈Ը̻ٙࠦྡ፫Ⴉجd฽މᔊఊeٜᝈdԨᔟ˸
                 ect ``intelligent Chinese phonetic input system'' (in                                                                      Selected Publications
                                                                                                                                            Selected Publications
                 cooperation with K. J, Chen), aimed at resolving a   ೯࢝̈ɓࡈœ฽ɽ̻ࠦྡٙᇞ׌စၑجf
                 major bottleneck in the computerization of Chinese
                 language -- the input method. A software resulted   ίਿΪҏΐɪdҢࡁ೯࢝̈ɓࢁ࢙፹စၑجd                                               1.  W. L. Hsu, "Maximum weight clique algorithms for circle graphs and   14.  W. L. Hsu and R. McConnell, “PC-trees and circular-ones arrange-
                 from this project, І್፩ɝج(GOING), achieved     ίྼ᜕Ⴌࢨʔ൴ཀ15%ٙઋرɨdঐ੄л͜clone ၾ                                                circular-arc graphs," SIAM J. Computing 14, (1985), 224-231.  ments”  Theoretical Computer Science 296(1), (2003), 99-116.
                 an accuracy close to 96% and has since revolution-  cloneʘගٙࠠᛌᗫڷࠇၑ̈዆ݬDNAҏΐʕ΢ࡈ                                          2.  W. L. Hsu, "Decomposition of perfect graphs," J. Combin. Theory 43,   15.  W. F. Lu and W. L. Hsu. “A Test for the Consecutive Ones Property on
                 ized the phonetic input for Chinese. Later, he moved                                                                     (1987), 70-94.                                   Noisy Data - Application to Physical Mapping and Sequence Assem-
                 into the research of Intelligent Agent on the Internet,   cloneٙɽߧЗໄfϤ̮dҢࡁл͜ˀᔧᕦύجணࠇ                                    3.  W. L. Hsu, "Recognizing planar perfect graphs," J. Assoc. Comput.   bly,” Journal of Computational Biology 10(5), (2004), 709-735.
                 and produced the Math. Problem Solving Agent in   ̈ɓࢁNMRஐͣሯഐ࿴৶฀࿁Ꮠ࢙ٙ፹စၑجf                                                 Machin. 34 (1987), 255-288.                    16.  K. P. Wu, H. N. Lin, J. M. Chang, T. Y. Sung, and W. L. Hsu, “HY-
                 1997, and a Chinese natural language Q & A system,   ίஐͣሯɚܓ٤ගഐ࿴ཫ಻ɪdҢࡁɰлٝ͜ᗆࢫ                                            4.  W. L. Hsu, "The coloring and maximum independent set problems on   PROSP: A Hybrid Protein Secondary Structure Prediction Algorithm
                 @skbots, in 1999. He is currently working on DNA   ٙҦ̷dਗ਼๟ᆽܓ౤؁Ց82%˸ɪfҢࡁί஢εഐ                                               planar perfect graphs," J. Assoc. Comput. machin., (1988), 535-563.  - a Knowledge-Based Approach,” Nucleic Acids Research 32(17),
                 and protein sequence analysis, proteomic knowledge                                                                     5.  C. Gabor, W. L. Hsu and K. Supowit, "Recognizing circle graphs in   5059-5065, (2004).
                 base and biological literature mining systems.  ࿴ཫ಻ਪᕚɪϓ̌ήഐΥə͛يٝᗆၾዚኜኪ୦Ҧ                                                   polynomial time," J. Assoc. Comput. machin., (1989), 435-473.  17.  Chun-Hung Lu, Shih-Hung Wu, LiongYu Tu, Wen-Lian Hsu, “On-
                                                                                                                                                                      2
                                                               ̷dਗ਼๟ᆽܓપΣอٙ৷ࢤf                                                            6.  W. K. Shih, W. L. Hsu and T. C. Chen, "An O(n logn) algorithm for   tological Support in Modeling Learners‘ Problem Solving Process,”
               •  Dr. Hsu has published in various top-notch journals                                                                     the Hamiltonian cycle problem on circular-arc graphs," SIAM J. Com-  Journal of Educational Technology & Society 8(4), 64-74, (2005).
                 in discrete mathematics, operations research and   ίІ್ႧԊ˙ࠦdҢࡁʃଡ଼ה೯࢝ٙءࠪІਗ                                                  put 21, (1992), 1026-1046.                     18.  Hsin-Nan Lin, Kuen-Pin Wu, Jia-Ming Chang, Ting-Yi Sung and
                 computer science. He has been invited to deliver                                                                       7.  W. L. Hsu, "Chinese parsing in a phoneme-to-character conversion   Wen-Lian Hsu, "GANA – A Genetic Algorithm for NMR Backbone
                 lectures at many international conferences. He   ᔷ਷οٙழ᜗œІ್፩ɝجd͍ᆽଟટڐ96%d                                                 system based on semantic pattern matching," International Journal   Resonance Assignment," Nucleic Acids Research 33(14), 4593-4601,
                 received the Outstanding Research Award from the   ಀᐏ੻1993ϋ௫̈ʕ˖༟ৃପۜᆤfІ್፩ɝجҷ                                              on Computer Processing of Chinese and Oriental Languages 40,   (2005).
                 National Science Council in 1991, 1994 and 1996   ᜊə਷ɛႩމءࠪ፩ɝ୆ᖟᗭኪٙᝈׂd౷ཁա                                                  (1995), 227-236.                               19.  Hsin-Nan Lin, Jia-Ming Chang, Kuen-Pin Wu, Ting-Yi Sung and Wen-
                 and was elected as an outstanding research fellow   Ցɽ଺ٙฌ͜fί2000ϋ3˜10໮પ̈ၣ༩е൬ɨ                                          8.  W. L. Hsu, "O (mn) algorithms for the recognition and isomorphism   Lian Hsu, "A knowledge-based hybrid method for protein secondary
                 by the NSC in 1999. He was the recipient of the fi rst                                                                    problems on circular-arc graphs," SIAM J. Comput 24, (1995),   structure prediction based on local prediction confi dence," Bioinfor-
                 œҽ਷ཻ߈ͩᆤ for his contribution in natu-        ༱dίɓ඄ʘʫϞՇຬεɛίPC Homeၣ१ɨ༱d                                                  411-439.                                         matics 21, 3227-3233, (2005).
                 ral language processing systems. He has been the   ৷֢הϞɨ༱ழ᜗ٙୋɚΤdͦۃᐼɨ༱ϣᅰʊટ                                              9.  W. L. Hsu and J. P. Spinrad, "Independent sets in circular-arc graphs," J.   20.  Tzong-Han Tsai, Shih-Hung Wu, Wen-Chi Chou, Yu-Chun Lin, Ding
                 conference chairs of ISAAC'91 and COCOON'98   ڐɓϵຬfҢࡁ̤ɓධࠠࠅٙϓ؈݊d೯࢝̈ɓࢁ                                                     Algorithms 19, (1995), 145-160.                  He, Ting-Yi Sung, Wen-Lian Hsu, “Various Criteria in the Evaluation
                 and has been involved in the editorship of the fol-  œІ್ႧԊႧจʱؓٙˏᏗ˸ʿ޴ᗫٙœ౽ᅆۨ                                            10.  W. K. Shih and W. L. Hsu, "A new planarity test," Theoretical Com-  of Biomedical Named Entity Recognition,” to appear in BMC Bioin-
                 lowing journals: Journal of Information Science                                                                          puter Science 223, (1999), 179-191.              formatics.
                 (1995-2001), International Journal of the Founda-  ٝᗆڌ༺ӻ୕(InfoMap)d̙˸ቇ͜׵஢εᏐ͜                                          11.  W. L. Hsu and T. H. Ma, "Substitution decomposition on chordal   21.  Kuen-Pin Wu, Jia-Ming Chang, Jun-Bo Chen, Chi-Fon Chang,
                 tion of Computer Science (1993-2002), Information   ӻ୕ٙٝᗆ၍ଣfί2005ϋ˚͉؇ԯᑘБٙୋɓ                                              graphs and its application," SIAM J. Comput. 28, (1999), 1004-1020.   Wen-Jin Wu, Tai-Huang Huang, Ting-Yi Sung and Wen-Lian Hsu,
                 Processing Letters (2001-), International Journal of   ֣œʕ˖ਪഈӻ୕ˢᒄdҢࡁྼ᜕܃ᐏ੻9ඟʕ                                          12.  W. L. Hsu, "A simple test for the consecutive ones property", J. Algo-  “RIBRA-an Error-Tolerant Algorithm for the NMR Backbone Assign-
                 Bioinformatics Research and Applications (2004-).   ୋɓΤfҢࡁ͍ίਗ਼வࢁӻ୕Ꮠ͜Ց͛ي༟ৃٙ˖                                               rithms 42, 1-16, (2002).                         ment Problem,” to appear in Journal of Computational Biology; also,
                 He was the president of the Artifi cial Intelligence                                                                    13.  J. L. Tsai and W. L. Hsu, “Applying an NVEF Word-Pair Identifi er to   in Proceedings of RECOMB’05.
                 Society in Taiwan (2001-2002). In 2006, he was   ᘠઞਖٙ޼ӺɪfϤ̮d2006ϋҢࡁਞ̋SIGHAN                                              the Chinese Syllable-to-Word Conversion Problem,” in Proceedings of
                 elected an IEEE Fellow.                       ʕ˖ᓙ൚ˢᒄdίCity UႧࣘࢫɪᐏ੻13ඟʕୋɓ                                                 COLING’02, Taipei, (2002).
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