TIGP -- Information hidden in a single structure - how to derive sequence conservation without doing sequence comparison?
- 講者黃鎮剛 博士 (交通大學生物資訊所)
邀請人：許聞廉 - 時間2012-04-05 (Thu.) 14:00 ~ 15:10
- 地點資訊所新館106演講廳
摘要
Our recent work showed that it is possible to derive information about function, dynamics and evolution directly from a single protein structure. This can be done without using a mechanical model or methods based on structure or sequence comparison. Our results show that a protein structure is more than just a scaffold holding residues in place and that there is a meaning in every twist and turn in a protein structure.